8:30 am Registration & Morning Coffee
9am-12pm Workshop A
Navigating Immunogenicity Challenges in Antibody & Fusion Protein Engineering
Synopsis
This workshop will provide a comprehensive overview, from risk assessment to innovative predictive modeling and testing methodologies, ensuring participants are well-equipped to navigate and mitigate immunogenicity concerns.
Join this workshop to:
- Discuss recent challenges and innovations in understanding and managing immunogenic responses • Uncover practical approaches to assess and mitigate the risk of immunogenicity during different stages of development
- Explore case studies illustrating successful strategies or challenges faced in addressing immunogenicity risks
- Discover the latest technologies, including artificial intelligence and machine learning, in predictive modeling of immunogenicity
- Evaluate the reliability of current testing practices, challenges faced, and potential improvements or innovations in toxicity assessment
- Gain insights into regulatory expectations and considerations regarding immunogenicity in antibody and fusion protein development
12:00 pm Lunch Break & Networking
1pm-4pm Workshop B
Exploring Strategies for Successful Stability: From Formulation Engineering to Advanced Analytics
Synopsis
Mastering the stability of biopharmaceuticals is paramount for ensuring therapeutic efficacy, patient safety, and successful product development. This workshop brings together crucial aspects of formulation optimization and advanced analytical techniques to empower participants in navigating the challenges associated with protein stability for antibodies and fusion proteins.
Attend this workshop to:
- Uncover the pivotal role of formulation optimization in preserving protein stability and showcase successful formulations that have mitigated aggregation risks while maintaining therapeutic efficacy
- Discuss the delicate balance between engineering for stability and preserving the biological activity of therapeutic proteins
- Explore advanced analytical techniques (size-exclusion chromatography, dynamic light scattering, mass spectrometry) for detecting and characterizing protein aggregates
- Emphasize the importance of an integrated approach, combining process optimization and analytical vigilance, to ensure the quality and safety of biopharmaceuticals